Echo 525 Liquid Handler

Für Flüssigkeitstransfers mit hohen Volumina

  • Entwickelt für Reagenzientransfers von biochemischen und genomischen Proben
  • Verbesserung der Datenqualität bei gleichzeitiger Einsparung von Reagenzienkosten
  • Reagenzienreservoir für den Transfer von Reagenzien mit größerem Volumen

Explore Echo 525 Models

Liquid Handling Reimagined

Introducing the Echo 525 Liquid Handler, the first rapid acoustic liquid handler designed specifically for biochemical and genomics reagent transfer. The Echo 525 Liquid Handler and the Echo Software Applications enable scientists to spend more time looking at data. Protocol creation and implementation in the Echo Software Applications are fast and does not require extensive training. Designed for use with the Echo System, the Access Laboratory Workstation expands the Echo 525 Liquid Handler's utility and further frees up time.

Echo 525 Liquid Handler Features

Key Benefits

  • Highly precise and accurate low volume transfers enabling assay miniaturization
  • Builds assays 50–100 times faster than traditional liquid handlers giving the lab higher capacity from one instrument
  • Suite of Echo Software Applications guide creation of complex protocols for a variety of applications
  • Eliminates pipetting variances that affect assay success
  • Integrates into the Labcyte Access Laboratory Workstation for increased throughput

Build Complex Assays Quickly

The flexibility, speed, accuracy, and precision of the Echo 525 Liquid Handler enable researchers to build assays that are not possible with traditional liquid handlers. The use of acoustic sound energy removes the traditional boundaries of tip and pin tool based liquid handlers. Transfer variable fluid heights and viscosities from one source plate to enable rapid assay creation in one fluid transfer run. Say goodbye to fixed plate designs as the Echo Liquid Handler moves fluids from any well to any well enabling researchers to design the experimental plates they need to make new discoveries.

Efficiently Transfer Build Reagents with Echo Qualified Reservoir

Assay assembly and the transfer of one reagent to many wells is simplified using the Echo Qualified Reservoir. With the capability of transferring up to 2.5 mL from each micro-well, you can build your assay without requiring an instrument change – saving time and money.

Flexible and Reliable Transfer of Genomic Reagents

The Echo 525 Liquid Handler transfers a wide range of fluids during one transfer including distilled water, buffers, nucleic acids, and reagents containing up to 50% glycerol. With its versatile fluid range, transfer volume range, any well to any well transfer capability, and powerful applications software the Echo 525 Liquid Handler supports a wide range of genomic assay workflows:

  • Gene Synthesis
  • PCR and qPCR assay set-up
  • RNA and DNA NGS sequencing workflows
  • Sanger sequencing assay set-up
  • Single-cell sample preparation

Acoustic Technology Video

 

Watch the Echo acoustic droplet ejection (ADE) technology in action. Sound waves eject precisely-sized droplets from the source plate onto the destination plate suspended above.

Echo 525 Acoustic Liquid Handler Specifications

Drop volume 25 nL
Volume transfer range 25 nL – 5 µL one well to one well
Transfer accuracy <10% deviation from target volume
Transfer precision <8% CV
Reagents supported PCR and qPCR reagents, synthetic biology reagents, NGS reagents, primers and probes, cell culture media, proteins, nucleic acids, up to 50% glycerol, serum, plasma, and antibodies
Source labware compatibility EchoQualified 384 Polypropylene, 384 Polypropylene Plus, Reservoir, Microplates
Destination labware compatibility All Echo Qualified Microplates and most ANSI-compliant/SBS-standard microplates in 96-, 384-well formats 8 -16 mm in height. Use of 1536-well plates as destination plates is application dependent
Dimensions 53.9 cm width x 68.3 cm depth x 92.5 cm height (21.2 x 26.9 x 36.4 inches)
Weight 128 kg (283 lbs)
Working envelope Additional 25.4 cm (10 inches) on top, 2.5 cm (1 inch) on sides, 7.6 cm (3 inches) at front, 30.5 cm (12 inches) at back
Electrical AC 120V, 50/60 Hz, 10 A or AC 230V, 50/60Hz, 5 A
Operating temperature 21°C ± 5°C (70°F ± 9°F)
Vacuum House supply minimum 200 Torr (266 mbar, 22 inches Hg Vac)
OR
Standalone vacuum with surge tank, minimum pump speed 2.0 m3/hr (70.68 cu ft/hr), minimum pressure 100 Torr (133 mbar, 26 inches Hg Vac)
Fluid class calibration No calibration needed

Content and Resources

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Miniaturized Illumina Nextera XT Library Prep using an Integrated Biomek i5 and Echo 525 Liquid Handling Workstation Alex Pierson and Shilpa Parakh from Beckman Coulter Life Sciences present their work on Miniaturized Illumina Nextera XT Library Prep using an Integrated Biomek i5 Multichannel and Echo525 Liquid Handling Workstation at ASHG 2019 in Houston, TX.
Off-the-shelf, Echo-based DNA Assembly Automation presented by George McArthur, Arzeda @SLAS2020 In this talk, George describes how his team transformed a series of arduous, complex, time-consuming and error-prone laboratory tasks into an effortless, straightforward, fast and mistake-free workflow using a combination of accessible software and hardware automation.&nbsp;
5 Years of high-throughput strain engineering with the Echo: lessons from Zymergen Automation presented by Christopher Bremner, Automation Engineer, Zymergen @SLAS2020 Zymergen has used the Echo Liquid Handler to automate strain engineering for many years now. In this talk, Chris reflects on some lessons learned during early Echo usage, provides some tips to maximize throughput of your Echo device, and showcases how Zymergen currently use Echo devices in their workflows.
Biomek i-Series and Echo Acoustic Liquid Handler Integrated Workstation This video highlights the Biomek i-Series and Echo Acoustic Liquid Handler Integrated Workstation
Cell-free and Acoustic Liquid Handling are Helping Tierra Disrupt Natural Product Discovery If you want to disrupt the natural products market, try combining acoustic liquid handling technology with advances in cell-free approaches. In this webinar, Zachary Sun, CEO of Tierra Biosciences (formerly Synvitrobio), shares how his company is doing just that using the Echo Liquid Handler