CD107a (LAMP-1) Antigen

The CD107a antigen is the heavily glycosylated 110 kDa lysosomal-associated membrane protein, LAMP-1. Together with LAMP-2, they are the mayor glycoproteins on the membrane of lysosome granules. CD107a molecule is ubiquitously found as intracellular antigen. It is also expressed on the surface of activated platelets, PHA activated, a few monocytic cell lines, and fetal thymus stromal cells. It has been described as a marker of cytotoxic CD8+ Tcell degranulation and of NK cell functional activity. As platelet activation marker, it has characteristics of an adhesive molecule. A minor fraction (<2%) of LAMP-1 is associated with the plasma membrane of most nucleated cells, presumably as a result of selective exchange of lysosomal and plasma membranes. Increased surface expression of LAMP-1 has been observed on transformed cells of high metastatic potential, and on embryonic cells.


 Clone: H4A3  Isotype: IgG1 Mouse

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Product Line Specifications

Format Liquid
Specificity CD107a
Form Pacific Blue*
Clone H4A3
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B13978

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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