CD11a Antigen

CD11a (αL integrin, LFA-1 α chain) is a member of the integrin family. Like some other leucocyte integrins (CD11b, CD11c, CD11d), CD11a is non-covalently associated with the β2 integrin subunit CD18. CD11a is a transmembrane glycoprotein of 170 kDa, mainly expressed by leucocytes including monocytes, macrophages, neutrophils, eosinophils, basophils, B and T lymphocytes. Activated platelets also express CD11a and CD18. LFA-1 (CD11a/CD18) promotes homotypic adhesion between lymphoid cells and heterotypic adhesion of leucocytes to the vascular endothelium. LFA-1’s known ligands are Intercellular Adhesion Molecules (ICAM): ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).


 Clone: 25.3  Isotype: IgG1 Mouse

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Product Line Specifications

Format Liquid
Specificity CD11a
Form FITC
Clone 25.3
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced IM0860U

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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