CD161 (NKR-P1A) Antibodies

The CD161 antigen is also designated as the NKR-P1A molecule. CD161 is a type II integral membrane protein expressed as a monomer of 44 kDa or as a disulphide-linked homodimer of 80 kDa. The carboxy-terminal extracellular domain is homologous to Ca2+-dependent (C-type) lectin superfamily. CD161 is an activatory NK receptor, but in contrast with other NK receptors such as KIR (p58, p70, p140) and CD94/NKG2, CD161-mediated activation is not HLA-dependent. CD161 is expressed on all NK cells and on sub-populations of T lymphocytes.
Clone: 191B8 Isotype: IgG2a Mouse
The 191B8 antibody partially blocks the spontaneous NK cytotoxicity in the P815 model.
Resources + Tools
FAQs Panel Design Product Listing Quality Standards Request a Quote

Explore CD161 Antibodies

Content and Resources

Building IVDR-compliant panels for haematological disorders Diagnostic purpose of the IVDR conjugated antibodies
Building IVDR compliant panels for haematological disorders wallchart Diagnostic purpose of the IVDR conjugated antibodies
IVDR: a new era for In-Vitro Diagnostic Medical Devices BEC Marseille IVDR team, in the framework of the IVDR Global program, has established and deployed a robust project plan to fulfill IVDR requirements of more than 230 IVD CE marked products for May 2022
How do I preserve sensitivity? Poster - How to preserve sensitivity
Immunophenotyping reference table - For haematopoietic malignancies Poster - Immunophenotyping reference table - For haematopoietic malignancies