CD39 Antigen

The CD39 molecule, known as ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1), is a 70-100 kDa integral membrane glycoprotein with two transmembrane domains. It belongs to the family of the primary enzymes responsible for cell surface nucleotide hydrolysis, with ATPase and ADPase activity. CD39 antigen is expressed on activated lymphocytes, regulatory T cells, B cells, and dendritic cells. It is involved in control of the extracellular nucleoside triphosphate pool (NTP), suppression of inflammation and control of platelet activation. The coordinated expression of CD39/CD73 on Tregs and the adenosine A2A receptor on activated T effector cells generates immunosuppressive loops. In human studies, it has been reported that CD4+CD25-CD39+ T cells are T inducers.


 Clone: BA54  Isotype: IgG1 Mouse

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Product Line Specifications

Format Liquid
Specificity CD39
Form PC5.5
Clone BA54
Isotype IgG1 Mouse
Target Species Human
Item Specifications Referenced B55385

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


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