CD42a Antigen

The CD42a antigen (GPIX) is a single-chain transmembrane glycoprotein of 22 kDa that forms a noncovalent complex with CD42b, CD42c and CD42d (GPIbα, GPIbβ, and GPV). The CD42a expression is restricted to platelets and megakaryocytes. The GPIb-IX-V complex is the platelet receptor for von Willebrand factor and is known as von Willebrand's factor-dependent adhesion receptor. Although GPIb-IX-V primarily functions as a platelet receptor for von Willebrand factor (VWF), it can also bind to other ligands present in circulation such as thrombin, P-selectin, integrin αMβ2, factor XI, factor XII, high- molecular-weight kininogen, as well as a number of snake venom proteins.

 Clone: SZ1  Isotype: IgG2a Mouse

The SZ1 monoclonal antibody reacts with the CD42a-d complex but does not recognize GPIb or GPIX individually.

Product Line Specifications

Format Liquid
Specificity CD42a
Clone SZ1
Isotype IgG2a Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced IM1757U

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 

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