IL-4-PE, MP4-25D2, 2 mL, ASR

Product No:C76793

Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4, IL-5, IL6 and IL-10.

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C76793_IL-4-PE, MP4-25D2, 2 mL, ASR

Spezifikationen

Target Species Human
Specificity IL-4
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone MP4-25D2
Isotype IgG1 Rat
Cross Reactivity Equine, MP4-25D2 cross reacts with: Porcine
Volume 2 mL