7-AAD Viability Dye is a ready-to-use reagent allowing discrimination of viable from non viable cells using flow cytometry. It is composed of 7-Amino-Actinomycin D (7-AAD) which intercalates between cytosine and guanine bases of the DNA. The maximum absorption of the 7-AAD / DNA complex is situated in the green spectral region, compatible with argon laser equipped-cytometer (excitation wavelength of 488 nm). The deep red fluorescence emission of 7-AAD (635 to 675 nm) makes the use of this probe easier in combination with fluorescein isothiocyanate (FITC) and phycoerythrin (PE) conjugated antibodies because, in contrast to propidium iodide (PI), the 7-AAD / DNA complex shows lower spectral overlap with FITC and PE.
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NOT ALL PRODUCTS ARE AVAILABLE IN ALL COUNTRIES. PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS The listed regulatory status for products correspond to one of the below: IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use." ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagent. Analytical and performance characteristics are not established." CE-IVD, CE: Products intended for in vitro diagnostic use and conforming to the In Vitro Diagnostic Regulation (IVDR) (EU) 2017/746. (Note: Devices may be CE marked to other directives.) RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures." LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only." No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.