Cydem VT System: Instrument Features​

Offering the capabilities to screen more top clones in cell line development, and freedom to walk away from the instrument for at least three days, the Cydem VT Automated Cell Culture System leverages the advantages of automation and adds what’s been missing: insights. It screens clones under conditions close to biomanufacturing production, while collecting vital data on cell growth and productivity all along the way.

 

Integrated bioreactor module

  • Cultivate 96 clones in 24-deep-well bioreactor plates in parallel
  • Online monitoring of pH, DO, and biomass
  • Unique gassing chip for well-individual gassing control
  • Maintain optimal pH and DO levels in your cultivations

Integrated cell count and viability module

  • Regular updates of cell count and viability throughout your entire experiment
  • Accurate and precise measurements with low sample volume (43 μL)
  • Utilizes our well-known Vi-CELL BLU Analyzer technology
 

Integrated titer module

  • Regular monoclonal antibody (mAbs) titer measurements
  • Small sample volume (10 µL)
  • Learn more about the productivity of your clones
  • Make informed decisions about your clone selection
 

Integrated liquid handler

  • Automate your top clone screening
  • Run more controlled fed-batch conditions and reduce the risk of selecting suboptimal clones
  • Automated inoculation and cell density normalization
  • Schedule builder for analysis, feeding strategy, and pH control

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3-Day Walk-Away Automated Operation with Auto-Normalization of Cell Density

  • Fully integrated solution with on-deck cell count, cell viability, mAbs titer, pH, and DO measurement

  • 3-day walk-away automated operation

  • Automated seeding of cell cultures

  • Schedule builder for analytical measurements, feeding strategy, and pH control

  • Centralized data on one instrument with the ability to easily export in .csv format

  • Single point of contact for sales, service, and technical support for the entire system, consumables, and reagents

Clone screening of 96 clones over 14 days. Viable cell density and mAbs titer displayed over the course of the experiment. For a better overview, 10 clones with different growth and productivity performances were selected.

Read about Cydem VT System Applications


valitatiter application note
 
Application Note
Introducing the Cydem VT Automated Cell Culture System: A high-throughput platform for fast and reliable clone screening experiments

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Application Note
Efficient clone screening with increased process control and integrated cell health and titer measurements with the Cydem VT Automated Cell Culture System

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Download the Cydem VT System Brochure

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Brochure

The Cydem VT Automated Cell Culture System combines multiple trusted Beckman Coulter technologies into one advanced platform that empowers lab managers with a far more effective, higher-throughput method for top clone screening in cell line development—offering increased confidence that promising clones don’t get overlooked in the process of consistently selecting the best. Download the brochure to learn more.

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